I-antibody engathathi hlangothi

Isithombe Esifakiwe Se-Antibody Engathathi hlangothi

Incazelo emfushane:

I-SARS-CoV-2 igciwane le-RNA elimboziwe futhi elinemicu eyodwa, eliwuhlobo lwe-beta.cov emndenini we-coronaviridae.I-1ts genome RNA ihlanganisa iphrotheni engaphindaphindekiyo kanye namaprotheni esakhiwo amaningana, okuhlanganisa ama-spike(ama), imvilophu(E), ulwelwesi(M) kanye nama-nucleocapsid(N) amaprotheni.

Thumela i-imeyili kithi

Imininingwane Yomkhiqizo

Omaka bomkhiqizo

I-Pathogenesis:

Iphrotheni ye-S inesibopho sokubophezela amagciwane kanye nokungena kumaseli abamba , ahlanganisa amayunithi amabili asebenzayo, i-s1 kanye ne-s2 kanye nesizinda esibopha isamukeli (RBD) sitholakala phakathi kwamayunithi angu-s1. I-RBD ye-SARS-CoV-2 S protein iyasebenzisana nge-angiotensin eguqulayo i-enzyme 2 (i-AcE2) edala izinguquko ezihambisanayo kuyunithi ye-s2 ephumela

ekuhlanganisweni kwegciwane kanye nokungena kuseli eliqondiwe .Ama-proteases ayimfihlo abantu, njenge-TMPRss2 kanye ne-furin, atholakala kuma-virally.target cells.

Lawa ma-protease athuthukisa ukungena kwegciwane kumaseli aphethe ngokusebenzisa i-proteolysis yawo womabili amaprotheni e-s1, s2, kanye ne-AcE2.

Ukusetshenziswa okuhlosiwe:

I-Anti SARS-CoV-2 Neutralizing Antibody Rapid Test Kit yakhelwe ukutholwa kwekhwalithi ye-SARS-CoV-2 amasosha omzimba angathathi hlangothi kumasampula egazi lomuntu.I-SARS-CoV-2 Neutralizing antibody iwuphawu olubalulekile lokuhlola ukusebenza kwemigomo ye-SARS-CoV-2.I-reagent eyenzelwe ukunciphisa ukutholwa kwe-antibody kumasampuli avela kubantu ngabanye ngemva kokujova umgomo noma ukululama ku-coV1D.19.Ikhithi izosiza futhi ophenyweni lwamanje lwe-coV1D.19 lokuvama kwe-sero-prevalence, ukuhlolwa kokuvikeleka komhlambi, ukuphila isikhathi eside kokugonywa kokuzivikela, ukusebenza ngempumelelo kwemithi yokugoma eyahlukene kanye nokulandela umkhondo ukutheleleka ezilwaneni.

izimo zokugcina kanye Nokusebenza:

Wonke ama-reagents alungele ukusetshenziswa njengoba enikeziwe.Amakhithi e-reagent angavuliwe azinzile ku-4"c ～30"c izinyanga ezingama-24 ngokwesikhashana.I-1t kufanele isetshenziswe phakathi nehora elingu-1 uma isikhwama sesivuliwe.Ungayiqandi ikhithi noma uveze ikhithi ngaphezu kuka-37"c ngesikhathi uyigcina.

Ukucaciswa:

1 ukuhlolwa / ibhokisi;5 ukuhlolwa / ibhokisi;25 ukuhlolwa / ibhokisi;50 ukuhlolwa / ibhokisi.

Inqubo Yokuhlola:

Ungasivuli isikhwama uze ulungele ukwenza isivivinyo, futhi ukuhlolwa kwe-single.use kuphakanyiswa ukuthi kusetshenziswe ngaphansi komswakamo ophansi wendawo (RHs70%) phakathi nehora elingu-1.

1.Vumela zonke izingxenye zekhithi nezifanekiso ukuthi zifinyelele izinga lokushisa legumbi phakathi kuka-18"c～26"c ngaphambi kokuhlolwa.2.Khipha ikhadi lokuhlola esikhwameni se-foil bese ubeka endaweni ehlanzekile eyomile.

3.1khomba ikhadi lokuhlola lesifanekiso ngasinye.

4.Sebenzisa i-dropper ukuletha iconsi eyodwa (i-1) ye-serum, i-plasma noma amasampula egazi eliphelele (40uL) emthonjeni wesampula ekhadini lokuhlola, kulandelwa ithonsi elilodwa lesampula yebhafa.

5.qala isibali sikhathi bese ufunda umphumela ngemizuzu eyi-15.

Ukuhunyushwa komphumela wokuhlola:

1tolika umphumela wokuhlolwa ngokweshadi lombala elilandelayo (Njengezansi).

1.1f ukushuba kombala kungaphansi kune-G4, okubonisa ukuthi ukugxilwa kwe-antibody engathathi hlangothi kukhulu kuno-200 PRNT50 2.1f ukushuba kombala kuphakathi kwe-G4 ne-G6, okubonisa ukuthi ukugxiliswa kwe-antibody engathathi hlangothi cishe ku-100 PRNT50 3.1f ukushuba kombala kuseduze ne-G7 , okubonisa ukuthi ukugxila kuwukwenza amasosha omzimba angathathi hlangothi ngu-50 PRNT50

4.Umkhawulo wokutholwa ngu-50 PRNT50

5.f ukushuba kombala kunamandla kune-G7, khombisa umphumela ongemuhle.

Okwedlule: I-Automatic Digital Wrist Blood Pressure Monitor

Olandelayo: I-Brochure-PocRoc®SARS-CoV-2 Antigen Rapid Test K0429